Research

At the Chair of Biomaterials, different model systems of fibrous protein biopolymers are studied, among them spider and insect silks, as well as collageneous mussel byssus threads. A further focus is on analysis and production of peptides and hybrid materials. The starting point always is the understanding of the molecular interplay and assembly mechanisms of the underlying peptides and proteins, as well as their impact on the structure-function relationships and material properties. Mimetic versions of the fibrous proteins are recombinantly produced, and their physico-chemical properties are thoroughly characterized. The recombinantly produced proteins are processed by variable methods into various material forms for technically relevant applications in pilot plant scale. The expertise of an interdisciplinary team covers six topics:

• protein analytics

• molecular biology / design of molecules

• recombinant protein production („white biotechnology“)

• functionalization and modifcation of proteins

• process technology (spinning, casting, coating, microfluidics, 3D printing/biofabrication a.o.)

• cell biology

Due to morphological variability, outstanding mechanical propterties, biocompatibility, biodegradability, as well as ease of functionalization biopolymers as spider silk and mussel collagens posess a huge appllication potential. The Chair of Biomaterials acts as an link between industry and scientific research, developing innovative high-performance materials for technical and medical applications. The scope of applications ranges from fine dust filter materials, special textiles, to cosmetics, wound repair, implant coating and drug delivery systems. Financial support is acknowledged by: Europäische Union (EU EFRE) | Deutsche Forschungsgesellschaft (DFG) | Fonds der Chemischen Industrie | Bundesministerium für Bildung und Forschung (BMBF) | US Army Research Office | Bayerisches Staatsministerium für Umwelt und Gesundheit (StMUG)

Zhanbassynova, Ainur

Diplom- / Masterstudierende

Rudisch, Christoph

Diplom- / Masterstudierende

Dr. Jalan, Abhishek

Group Leaders

Michel, Manuel

Diplom- / Masterstudierende

Häußermann, Angelika

Diplom- / Masterstudierende

Döhla, Kathrin (M.Sc.)

DoktorandInnen

Sprenger, Lys (M.Sc.)

DoktorandInnen

Hahn, Jonas (M. Sc.)

DoktorandInnen

Vsanthakumar Sindhu, Gadha Vasanth

Diplom- / Masterstudierende

Ebbinghaus, Thomas (M.Sc.)

DoktorandInnen

Mohotti, Supun

Graduate Students

Rajwar, Ashish (M.Sc.)

Graduate Students

Heinritz, Christina (M. Sc.)

Graduate Students

Dr. Kharaziha, Mahshid

guest researchers

Special Actor "Paul", MOOC Biofabrication

Diploma- / Master students

Special Actor "Emma", MOOC Biofabrication

Diploma- / Master students

Schiller, Tim (M.Sc.)

Graduate Students

Santiago-Rivera, Edgardo (M.Sc.)

Graduate Students

Ng, Xuen (M.Sc.)

Graduate Students

Claussen, Julia (M.Sc.)

DoktorandInnen

Sommer, Christoph (M.Sc.)

Graduate Students

Pittel, Nicole (MTA)

Technische Angestellte

Bin Zainuddin, Muhammad Shakir (M.Sc.)

Graduate Students

Schwägerl, Sabrina

Secretary

Dr. Scheibel, Melanie

Group Leaders

Mayer, Kai (M.Sc.)

Graduate Students

Schmidt, Andreas (BTA)

Technicians

Pellert, Alexandra (MTA)

Technicians

Jasinski, Julia (M.Sc.)

Graduate Students

Trossmann, Vanessa (M.Sc.)

Graduate Students

Hopfe, Charlotte (M.Sc.)

Graduate Students

Dr. Bargel, Hendrik

Group Leaders

Bodner, Andrea

Secretary

Diehl, Johannes (BTA)

Technicians

Prof. Dr. Scheibel, Thomas

Head of Department

Dr. Humenik, Martin

Group Leaders

Dr. Gruhn, Thomas

Group Leaders

Dr. Salehi-Müller, Sahar

Group Leaders

Biofabrication

Biofabrication is an interdisciplinary research field with the aim of generating functional tissue constructs. The basic components therefor are cells, matrix materials and growth factors. Principles and methods from medicine, natural sciences and engineering are combined to develop and apply a fundamental understanding of the relationship between the structure and function of tissues.

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Cell-Materials Interaction

Cell-based assays are an important part of biomaterial research for medical applications, as they allow conclusions to be drawn on cell viability and adhesion. Therefore, our research group focuses on the interaction and behaviour of a wide variety of cells and materials, at simulated body conditions and under the influence of electrical, chemical or mechanical stimuli.

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Fibers

The focus of this research group is the production of functional and high-performance fiber materials based on proteins. Fiber, yarn und fiber mats are produced using the following processing technologies: wet-, electrostatic- and biomimetic spinning as well as microfluidics.

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Hybrid Materials

Application of the self-assembly principles to control nano- and micro scaled structuring of biomaterials is in focus of our group.

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Protein Assembly/Processing

The research group “Protein Assembly and Processing” deals with research and development of various processing methods of protein materials and their applications.

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Protein Modification

This research group is focusing on production and analysis of recombinant spider silk proteins and their application-specific modification.

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Simulations of Mesostructured Materials

The group uses computer simulations and numerical methods for studying polymer and filament networks, colloid-polymer suspensions, and colloidal quasicrystals. Furthermore, we investigate solid state materials for alternative energy materials like thermoelectrics and thin film solar cells.

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Tissue Engineering

Working group Salehi focuses on developing and combining advanced biomaterials with microfabrication techniques. Designing and application of micro and nano features have been evaluated to engineer complex and functional tissue constructs. The modified structures will show improved physical, mechanical and biological properties.

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