At the Chair of Biomaterials, different model systems of fibrous protein biopolymers are studied, among them spider and insect silks, as well as collageneous mussel byssus threads. A further focus is on analysis and production of peptides and hybrid materials. The starting point always is the understanding of the molecular interplay and assembly mechanisms of the underlying peptides and proteins, as well as their impact on the structure-function relationships and material properties. Mimetic versions of the fibrous proteins are recombinantly produced, and their physico-chemical properties are thoroughly characterized. The recombinantly produced proteins are processed by variable methods into various material forms for technically relevant applications in pilot plant scale. The expertise of an interdisciplinary team covers six topics:

• protein analytics

• molecular biology / design of molecules

• recombinant protein production („white biotechnology“)

• functionalization and modifcation of proteins

• process technology (spinning, casting, coating, microfluidics, 3D printing/biofabrication a.o.)

• cell biology

Due to morphological variability, outstanding mechanical propterties, biocompatibility, biodegradability, as well as ease of functionalization biopolymers as spider silk and mussel collagens posess a huge appllication potential. The Chair of Biomaterials acts as an link between industry and scientific research, developing innovative high-performance materials for technical and medical applications. The scope of applications ranges from fine dust filter materials, special textiles, to cosmetics, wound repair, implant coating and drug delivery systems. Financial support is acknowledged by: Europäische Union (EU EFRE) | Deutsche Forschungsgesellschaft (DFG) | Fonds der Chemischen Industrie | Bundesministerium für Bildung und Forschung (BMBF) | US Army Research Office | Bayerisches Staatsministerium für Umwelt und Gesundheit (StMUG)


Biofabrication is an interdisciplinary research field with the aim of generating functional tissue constructs. The basic components therefor are cells, matrix materials and growth factors. Principles and methods from medicine, natural sciences and engineering are combined to develop and apply a fundamental understanding of the relationship between the structure and function of tissues.


Cell-Materials Interaction

Cell-based assays are an important part of biomaterial research for medical applications, as they allow conclusions to be drawn on cell viability and adhesion. Therefore, our research group focuses on the interaction and behaviour of a wide variety of cells and materials, at simulated body conditions and under the influence of electrical, chemical or mechanical stimuli.


Collagen - Structure


Collagen - Structure, Function and Biomaterials

Collagens are a family of human proteins containing the characteristic triple helix domain. They provide strength and elasticity to tissues and bind other proteins to regulate cell function and blood clotting. Our lab investigates how collagen primary sequence dictates foldability and the ability to interact with other proteins on a molecular level.



The focus of this research group is the production of functional and high-performance fiber materials based on proteins. Fiber, yarn und fiber mats are produced using the following processing technologies: wet-, electrostatic- and biomimetic spinning as well as microfluidics.


Function and Biomaterials


Funktion und Biomaterialien


Hybrid Materials

Application of the self-assembly principles to control nano- and micro scaled structuring of biomaterials is in focus of our group.


Kollagen – Struktur


Protein Assembly/Processing

The research group “Protein Assembly and Processing” deals with research and development of various processing methods of protein materials and their applications.


Protein Modification

This research group is focusing on production and analysis of recombinant spider silk proteins and their application-specific modification.


Simulations of Mesostructured Materials

The group uses computer simulations and numerical methods for studying polymer and filament networks, colloid-polymer suspensions, and colloidal quasicrystals. Furthermore, we investigate solid state materials for alternative energy materials like thermoelectrics and thin film solar cells.


Tissue Engineering

Working group Salehi focuses on developing and combining advanced biomaterials with microfabrication techniques. Designing and application of micro and nano features have been evaluated to engineer complex and functional tissue constructs. The modified structures will show improved physical, mechanical and biological properties.

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